Disclosed are systems and methods for a network slice profile management within 5G network infrastructures and operating environments. The disclosed systems and methods can provide mechanisms for automatically selecting slice profiles for specific applications, user profiles and/or experience modes. The disclosed systems and methods involve the novel implementation of specifically designated slice profiles within an universal software radio peripheral (USRP), from which network traffic from a device can be designated via selected slice profiles from the USRP based on types of user profiles being leveraged for application sessions from the user's device.