Invention Application
- Patent Title: ANTIBODY VARIABLE DOMAINS TARGETING THE NKG2D RECEPTOR
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Application No.: US18894660Application Date: 2024-09-24
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Publication No.: US20250019444A1Publication Date: 2025-01-16
- Inventor: Gregory P. Chang , Ann F. Cheung , Asya Grinberg , William Haney , Bradley M. Lunde , Bianka Prinz
- Applicant: Dragonfly Therapeutics, Inc.
- Applicant Address: US MA Waltham
- Assignee: Dragonfly Therapeutics, Inc.
- Current Assignee: Dragonfly Therapeutics, Inc.
- Current Assignee Address: US MA Waltham
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K16/32
Abstract:
Antibody heavy chain variable domains that can be paired with antibody light chain variable domains to form an antigen-binding site targeting the NKG2D receptor on natural killer cells are described. Proteins comprising an NKG2D antigen-binding site, pharmaceutical compositions and therapeutic methods thereof, including for the treatment of cancer, are also described.
Information query
