An electronic device and method are provided. The method includes, in response to a result of a performed determination, between a processing-in-memory (PIM) operation and a non-PIM operation, being that a target operation included in an instruction set is the PIM operation, loading information regarding a PIM operation type of the target operation to a PIM operation register of an accelerator of the electronic device based on a performed determination that input data, for use in the target operation, is arranged in a memory of the accelerator according to a characteristic of the target operation, and controlling, using a PIM operation execution instruction, one or more PIM processing elements (PEs) of the memory to perform the target operation using the arranged input data and the information regarding the operation type loaded in the PIM operation register.