Invention Application
- Patent Title: CRYSTALLINE SALT FORM OF EP4 ANTAGONIST
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Application No.: US18719032Application Date: 2022-12-22
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Publication No.: US20250051285A1Publication Date: 2025-02-13
- Inventor: Farid Benayoud
- Applicant: Eisai R&D Management Co., Ltd.
- Applicant Address: JP Bunkyo-ku, Tokyo
- Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee Address: JP Bunkyo-ku, Tokyo
- International Application: PCT/US2022/053842 WO 20221222
- Main IPC: C07D231/20
- IPC: C07D231/20 ; A61K31/415

Abstract:
A crystalline free acid form of (S)-4-(1-(3-(difluoromethyl)-1-methyl-5-(3-(trifluoromethyl)phenoxy)-1H-pyrazole-4-carboxamido)ethyl)benzoic acid is provided. Methods of making and using the crystalline free acid form of (S)-4-(1-(3-(difluoromethyl)-1-methyl-5-(3-(trifluoromethyl)phenoxy)-1H-pyrazole-4-carboxamido)ethyl)benzoic acid are also provided.
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