An Android-based system for touch input handling is provided. The system includes an interactive hardware and an application processor. The interactive hardware includes a display panel and a touch panel that runs a touch firmware. The application processor is coupled to the interactive hardware, and runs an application program and a touch driver. The application processor further converts a hardware synchronization signal of the display panel into a software synchronization signal, and generates an application synchronization signal based on the software synchronization signal. Additionally, the application processor further generates an input synchronization signal that is synchronized with the application synchronization signal. The expiration of the input synchronization signal triggers the touch firmware to collect the touch event and propagate the touch event up to the application program through the touch driver.