Invention Application
- Patent Title: Dibenzoxanthene Quenchers, Uses, and Methods of Preparation
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Application No.: US18580853Application Date: 2022-07-21
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Publication No.: US20250092261A1Publication Date: 2025-03-20
- Inventor: Andrew Levitz , Scott Benson , Brian Evans , Khairuzzaman Bashar Mullah
- Applicant: Life Technologies Corporation
- Applicant Address: US CA Carlsbad
- Assignee: Life Technologies Corporation
- Current Assignee: Life Technologies Corporation
- Current Assignee Address: US CA Carlsbad
- International Application: PCT/US2022/074028 WO 20220721
- Main IPC: C09B57/14
- IPC: C09B57/14 ; C12Q1/686 ; G01N21/64

Abstract:
The present disclosure relates to dibenzoxanthene compounds that are efficient quenchers of fluorescence, for example in the far red and near infrared spectrum. Applications using the dibenzoxanthene quenching compounds and methods of making same are also described. Also disclosed is a method of detecting or quantifying a target nucleic acid molecule in a sample by polymerase chain reaction (PCR). The compounds have the following formula (I).
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