Invention Application
- Patent Title: HETEROARYL DERIVATIVE AND USES THEREOF
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Application No.: US18730491Application Date: 2023-01-19
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Publication No.: US20250101023A1Publication Date: 2025-03-27
- Inventor: Gu KONG , Ratnakar Reddy KUCHUKULLA , Su Min KIM , So Jeong MOON , Woo Young HUR , In Jeong HWANG
- Applicant: IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) , KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- Applicant Address: KR Seoul; KR Seoul
- Assignee: IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY),KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee: IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY),KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee Address: KR Seoul; KR Seoul
- Priority: KR10-2022-0009530 20220121,KR10-2022-0095624 20220801
- International Application: PCT/KR2023/000930 WO 20230119
- Main IPC: C07D473/34
- IPC: C07D473/34 ; A61K31/52 ; A61K31/5377 ; A61P35/00 ; C07D473/16 ; C07D473/40
Abstract:
The present invention relates to a heteroaryl derivative, a stereoisomer thereof, a hydrate thereof, a solvate thereof, or a pharmaceutically acceptable salt thereof, a method for preparing the same, and a pharmaceutical composition for preventing or treating cancer comprising the same as an active ingredient. The heteroaryl derivative of the present invention exhibits high inhibitory activity against overexpressed HER2, and thus, a pharmaceutical composition containing the same as an active ingredient can be usefully used for preventing or treating HER-2 positive cancer.
Information query
