发明授权
US3557103A 2-phenyl-4-tertiary aminoloweralkyl-2h-1,4-benzoxazin-3(4h)-ones
失效
2-苯基-4-叔丁基氨基甲基-3H-1,4-苯并恶嗪-3（4H） - 酮
- 专利标题： 2-phenyl-4-tertiary aminoloweralkyl-2h-1,4-benzoxazin-3(4h)-ones
- 专利标题（中）： 2-苯基-4-叔丁基氨基甲基-3H-1,4-苯并恶嗪-3（4H） - 酮
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申请号： US3557103D申请日： 1968-07-18
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公开(公告)号： US3557103A公开(公告)日： 1971-01-19
- 发明人: NORDIN IVAN C
- 申请人： PARKE DAVIS & CO
- 专利权人： Parke Davis & Co
- 当前专利权人： Parke Davis & Co
- 优先权： US74569568 1968-07-18
- 主分类号： C07D265/36
- IPC分类号： C07D265/36 ; C07D87/48
摘要：
NOVEL BENZOXAZINONE FREE BASE (I) AND ACID ADDITION SALT COMPOUNDS
2-PHENYL,4-(A=N-(CH2)N-)-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-3-
ONE
ARE PROVIDED BY CONDENSING 2-PHENYL-2H-1,4-BENZOXAZIN3(4H)-ONE WITH THE APPROPRIATE AMINOALKYL SIDE CHAIN IN EITHER ONE OR TWO STEPS WHERE B IS 3, 4 OR 5 AND -N=A IS A DIISOPROPYLAMINO, 2,5-DIMETHYL-1-PYRROLIDINYL OR 2,6DIMETHYLPIPERIDINO GROUP. THE PRODUCTS HAVE PHARMACOLOGICAL PROPERTIES AND ARE USEFUL ANTI-ARRHYTHMIC AGENTS.
2-PHENYL,4-(A=N-(CH2)N-)-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-3-
ONE
ARE PROVIDED BY CONDENSING 2-PHENYL-2H-1,4-BENZOXAZIN3(4H)-ONE WITH THE APPROPRIATE AMINOALKYL SIDE CHAIN IN EITHER ONE OR TWO STEPS WHERE B IS 3, 4 OR 5 AND -N=A IS A DIISOPROPYLAMINO, 2,5-DIMETHYL-1-PYRROLIDINYL OR 2,6DIMETHYLPIPERIDINO GROUP. THE PRODUCTS HAVE PHARMACOLOGICAL PROPERTIES AND ARE USEFUL ANTI-ARRHYTHMIC AGENTS.
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