发明授权
US3584014A Method for the preparation of (cis-1,2-epoxypropyl)-phosphonic acid and derivatives
失效
（CIS-1,2-环氧丙基） - 磷酸和衍生物的制备方法
- 专利标题： Method for the preparation of (cis-1,2-epoxypropyl)-phosphonic acid and derivatives
- 专利标题（中）： （CIS-1,2-环氧丙基） - 磷酸和衍生物的制备方法
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申请号： US3584014D申请日： 1969-06-02
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公开(公告)号： US3584014A公开(公告)日： 1971-06-08
- 发明人: FIRESTONE RAYMOND A , SLETZINGER MEYER
- 申请人： MERCK & CO INC
- 专利权人： Merck & Co Inc
- 当前专利权人： Merck & Co Inc
- 优先权： US82976769 1969-06-02
- 主分类号： C07F9/38
- IPC分类号： C07F9/38 ; C07F9/655
摘要：
A METHOD FOR THE PREPARATION OF (CIS-1,2-EPOXYPROPYL)PHOSPHONIC ACID AND ITS SALT AND ESTER DERIVATIVES, WHICH COMPRISES TREATING A ((1 - VINYLOXY) METHYL) PHOSPHONIC ACID OR A SALT OR ESTER THEREOF WITH A REAGENT CAPABLE OF EFFECTING RING CLOSURE. THE (CIS-1,2-EPOXYPROPYL) PHOSPHONIC ACID PRODUCT THUS OBTAINED AND ITS SALTS ARE ANTIBIOTICS WHICH HAVE UTILITY ASS ANTIMICROBIAL AGENTSS IN INHIBITING THE GROWTH OF GRAM-POSITIVE AND GRAM-NEGATIVE PATHOGENIC BATERIA.