SUBSTITUTED PHENYLTHIOAMIDE COMPOUNDS SUCH AS 2-(4CHLOROPHENYLTHIO)ACETAMIDINE; 2-(4 - RHLOROPHENYLTHIO)ACETAMIDOXIME; AND THEIR PHARAMACEUTICALLY-ACCEPTABLE SALTS ARE PREPARED BY THE REACTION OF A SUBSTITUTED PHENYLTHIOACETONITRILE WITH HYDROXYLAMINE HYDROCHLORIDE OR WITH METHANOL FOLLOWED BY AMMONIUM CHLORIDE. THE COMPOUNDS HAVE ANTIMICROBIAL ACTIVITY AND ALSO INHIBIT ADPINDUCED AGGREGATION OF BLOOD PLATELETS.