发明授权
US3814761A (2-pyrimidinylthio)alkanoic acids,esters,amides and hydrazides
失效
（2-PYRIMIDINYLTHIO）碱性酸，酯，氨基和水合物
- 专利标题： (2-pyrimidinylthio)alkanoic acids,esters,amides and hydrazides
- 专利标题（中）： （2-PYRIMIDINYLTHIO）碱性酸，酯，氨基和水合物
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申请号： US24026672申请日： 1972-03-31
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公开(公告)号： US3814761A公开(公告)日： 1974-06-04
- 发明人: SANTILLI A , SCOTESE A , TOMARELLI R
- 申请人： AMERICAN HOME PROD
- 专利权人： American Home Prod
- 当前专利权人： American Home Prod
- 优先权： US24026672 1972-03-31; US38443973 1973-08-01
- 主分类号： C07D239/06
- IPC分类号： C07D239/06 ; C07D239/38 ; C07D239/46 ; C07D239/56 ; C07D239/60 ; C07D405/06 ; C23F11/14 ; C07D51/36
摘要：
(2-PYRIMIDINYLTHIO)N ALKANOIC ACIDS, ESTERS, AMIDES AND HYDRAZIDES AS WELL AS VARIOUS 4- AND 6-SUBSTITUTED DERIVATIVES THEREOF AS DEPICTED BY THE STRUCTURAL FORMULA:
2-(Z-CO-(CH2)M-CH(-R)-S-),4-R1,5-R2,6-Y-PYRIMIDINE
IN WHICH R AND R2 ARE INDEPENDENTLY -H OR LOWER ALKYL; R1 IS -H, -HALO OR LOWER ALKOXY; Z IS -OH, OM, LOWER ALKOXY OR -(NH)P-NH2, WHEREIN P IS 0 TO 1 AND M IS AN ALKALI METAL, ALKALINE EARTH METAL OR AMMONIUM CATION; Y IS AN ARYL, AMINO OR SUBSTITUTED AMINO RADICAL; AND M IS AN INTEGER FROM 0 TO 2, EXHIBIT ANTI-LIPEMIC ACTIVITY IN WARM-BLOODED ANIMALS.
2-(Z-CO-(CH2)M-CH(-R)-S-),4-R1,5-R2,6-Y-PYRIMIDINE
IN WHICH R AND R2 ARE INDEPENDENTLY -H OR LOWER ALKYL; R1 IS -H, -HALO OR LOWER ALKOXY; Z IS -OH, OM, LOWER ALKOXY OR -(NH)P-NH2, WHEREIN P IS 0 TO 1 AND M IS AN ALKALI METAL, ALKALINE EARTH METAL OR AMMONIUM CATION; Y IS AN ARYL, AMINO OR SUBSTITUTED AMINO RADICAL; AND M IS AN INTEGER FROM 0 TO 2, EXHIBIT ANTI-LIPEMIC ACTIVITY IN WARM-BLOODED ANIMALS.
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