Primary amines may be cyclialkylated by treatment with a heterocyclic oxygen compound in the presence of a catalyst system comprising a polyheterocyclic amine having a nitrogen in the bridgehead position and a component selected from the group consisting of a halogen acid, a metal selected from Group VIII of the Periodic Table dispersed on an inorganic oxide support and a sulfonic acid-substituted divinyl benzene-styrene copolymer resin.