A DC amplifier circuit with transformer coupled isolation comprises a DC amplifier, an electronic switching element connected to the output terminal of the DC amplifier, a pulse generator for driving the electronic switching element, a small pulse transformer having a primary winding and secondary winding. To the primary winding of the small transformer pulsating signals from the electronic switching element are applied, and two substantially identical circuits each having a diode and a condenser in series are connected respectively across the primary winding and the secondary winding of the small pulse transformer. Means for feeding back the smoothed signals from the circuit across the primary winding of the small pulse transformer is connected to a negative input terminal of the DC amplifier.