发明授权
US3956492A Pharmaceutical compositions containing a
3-(amino-methylene)-5-phenyl-1,4-benzodiazepin-2-one and method of use
失效
含有3-(氨基 - 亚甲基)-5-苯基-1,4-苯并二氮杂-2-酮的药物组合物及其使用方法
- 专利标题: Pharmaceutical compositions containing a 3-(amino-methylene)-5-phenyl-1,4-benzodiazepin-2-one and method of use
- 专利标题(中): 含有3-(氨基 - 亚甲基)-5-苯基-1,4-苯并二氮杂-2-酮的药物组合物及其使用方法
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申请号: US532069申请日: 1974-12-12
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公开(公告)号: US3956492A公开(公告)日: 1976-05-11
- 发明人: Helmut Pieper , Gerd Kruger , Johannes Keck , Klaus-Reinhold Noll , Joachim Kaehling
- 申请人: Helmut Pieper , Gerd Kruger , Johannes Keck , Klaus-Reinhold Noll , Joachim Kaehling
- 申请人地址: DT Ingelheim am Rhein
- 专利权人: Boehringer Ingelheim GmbH
- 当前专利权人: Boehringer Ingelheim GmbH
- 当前专利权人地址: DT Ingelheim am Rhein
- 优先权: DT2234150 19720712; DT2324962 19730515
- 主分类号: A61K31/33
- IPC分类号: A61K31/33 ; A61K31/495 ; A61K31/535 ; A61K31/54
摘要:
Pharmaceutical dosage unit compositions containing as an active ingredient a compound of the formula ##SPC1##WhereinR.sub.1 and R.sub.2, which may be identical to or different from each other, are each hydrogen, cycloalkyl, phenyl, --A--YwhereinA is alkyl of 1 to 5 carbon atoms or alkenyl of 1 to 5 carbon atoms, andY is furyl, dialkylamino, hydroxyl, carbalkoxy or carbamido,Or, together with each other and the nitrogen atom to which they are attached, pyrrolidino, piperidino, hexamethyleneimino, morpholino, thiomorpholino, thiomorpholino-S-oxide or N'-alkylpiperazino,R.sub.3 is halogen, nitro or trifluoromethyl,R.sub.4 is hydrogen, halogen or trifluoromethyl, andR.sub.5 is hydrogen, alkyl, cycloalkyl-methyl, alkylamino-alkyl, dialkylamino-alkyl or trifluoromethyl-alkyl;And a method of using the same as sedatives, tranquilizers, muscle-relaxants and anticonvulsives.
公开/授权文献
- US5575500A Occupant protecting structures of vehicle body upper portions 公开/授权日:1996-11-19
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