发明授权
US3959256A 9-O-Alkanoyl-3"-O-alkanoyloxymethyl-SF-837 substance and the production
thereof
失效
9-O-烷酰基-3 {41-烷酰氧基甲基-SF-837物质及其制备
- 专利标题: 9-O-Alkanoyl-3"-O-alkanoyloxymethyl-SF-837 substance and the production thereof
- 专利标题(中): 9-O-烷酰基-3 {41-烷酰氧基甲基-SF-837物质及其制备
-
申请号: US505310申请日: 1974-09-12
-
公开(公告)号: US3959256A公开(公告)日: 1976-05-25
- 发明人: Shigeharu Inouye , Shoji Omoto , Katsuyoshi Iwamatsu , Taro Niida , Toyoaki Kawasaki , Takashi Tsuruoka
- 申请人: Shigeharu Inouye , Shoji Omoto , Katsuyoshi Iwamatsu , Taro Niida , Toyoaki Kawasaki , Takashi Tsuruoka
- 申请人地址: JA Tokyo
- 专利权人: Meiji Seika Kaisha, Ltd.
- 当前专利权人: Meiji Seika Kaisha, Ltd.
- 当前专利权人地址: JA Tokyo
- 主分类号: C07H17/08
- IPC分类号: C07H17/08
摘要:
A 9-O-alkanoyl-3"-O-alkanoyloxymethyl-SF-837 substance is now synthetized, which is a new compound useful in that this new 9-O-alkanoyl-3"-O-alkanoyloxymethyl derivative of the SF-837 substance exhibits an antibacterial activity comparable to that of the parent SF-837 substance but is advantageously free from the unpleasant bitter taste inherent to the SF-837 substance and is hence adapted for oral administration. A process of producing the 9-O-alkanoyl-3"-O-alkanoyloxymethyl-SF-837 substance is also provided, which comprises hydrolysing partially and selectively a 9,2'-di-O-alkanoyl-3"-O-alkanoyloxymethyl-SF-837 substance in an aqueous alkanol or aqueous acetone. The 9,2'-di-O-alkanoyl-3"-O-alkanopyloxymethyl-SF-837 substance may be prepared by reacting a 9,2'-di-alkanoyl- or O-mono-O-alkanoyl-3"-O-thiomethoxymethyl-SF-837 substance with an alkanoic anhydride which is exemplified by acetic anhydride or propionic anhydride in the specification.
公开/授权文献
- US5695663A Plasma cutting method and NC plasma cutting apparatus 公开/授权日:1997-12-09