发明授权
US3962248A Process for making 11-piperazino-diazepines, oxazepines, thiazepines and
azepines
失效
制备11-哌嗪二氮杂，氧化ES ES，，，ES ES ES ES ES ES ES ES
- 专利标题： Process for making 11-piperazino-diazepines, oxazepines, thiazepines and azepines
- 专利标题（中）： 制备11-哌嗪二氮杂，氧化ES ES，，，ES ES ES ES ES ES ES ES
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申请号： US553142申请日： 1975-02-26
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公开(公告)号： US3962248A公开(公告)日： 1976-06-08
- 发明人: Josef Schneider
- 申请人： Josef Schneider
- 申请人地址： NJ Hanover
- 专利权人： Sandoz, Inc.
- 当前专利权人： Sandoz, Inc.
- 当前专利权人地址： NJ Hanover
- 优先权： CH4898/72 19720404; CH4901/72 19720404
- 主分类号： C07D295/02
- IPC分类号： C07D295/02 ; C07D295/03 ; C07D333/20 ; C07D333/32 ; C07D513/04 ; C07D403/04 ; C07D413/04 ; C07D417/04
摘要：
This invention concerns a novel process for the preparation of 6-piperazinyl derivatives of morphantridine and corresponding ring-substituted and hereto analogues thereof, comprising reacting a compound of the formula: ##SPC1##Wherein A is benzene or thiophene, and X is --CH.sub.2 -- or a hetero atom or group, with a complex comprising titanium, zirconium, hafnium or vanadium and a corresponding piperazinyl derivative.The end products are in general known and useful as neuroleptics.
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