发明授权
US3965167A Crystalline ammonium N-acetyl-L-cysteinate and mucolytic process
失效
N-乙酰基-L-半胱氨酸结晶铵和粘液溶解过程
- 专利标题： Crystalline ammonium N-acetyl-L-cysteinate and mucolytic process
- 专利标题（中）： N-乙酰基-L-半胱氨酸结晶铵和粘液溶解过程
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申请号： US223352申请日： 1972-02-03
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公开(公告)号： US3965167A公开(公告)日： 1976-06-22
- 发明人: Eugene Emanuel Hamlow , Tellis Alexander Martin
- 申请人： Eugene Emanuel Hamlow , Tellis Alexander Martin
- 申请人地址： Evansville, Indiana 47721
- 专利权人： Mead Johnson & Company
- 当前专利权人： Mead Johnson & Company
- 当前专利权人地址： Evansville, Indiana 47721
- 主分类号： A61K31/195
- IPC分类号： A61K31/195 ; C07C101/04
摘要：
The ammonium salt of N-acetyl-L-cysteine is a relatively non-hygroscopic crystalline solid which renders it particularly useful for administration by insufflation in the treatment of bronchopulmonary disease. It is of use in a mucolytic process wherein bronchopulmonary mucus is contacted with solid ammonium N-acetyl-L-cysteinate utilizing only the energy of the inspiratory action of the inhaler.
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