Multi-component mixed filament, wherein at least two spinning materials having poor affinity are mixed and dispersed in unitary filament in a nebular configuration containing at least 50 stars at least in one portion of the cross-section of the filament and the nebular configuration continues substantially in the longitudinal direction of the filament is manufactured by subjecting said spinning materials to at least eight times of "joining and dividing step in different phase" repeatedly to layer-multiply said spinning materials so as to form a nebular configuration in the cross-section of the resulting filament and then extruding the resulting mixture from orifice in a spinneret. In this manufacture, the preferable combinations of said two spinning materials having poor affinity are polyamide-polyester, polyamide-polyalkylne oxide, polyester-polyalkylene oxide and polyamide-polyolefin.