发明授权
- 专利标题: Basically substituted heterocyclic compounds
- 专利标题(中): 基本上取代的杂环化合物
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申请号: US488578申请日: 1974-07-15
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公开(公告)号: US3987036A公开(公告)日: 1976-10-19
- 发明人: Heinz Bender , Otto Grawinger , Adolf Stachel, deceased , by Ingeburg Lydia Katharina Stachel, heiress , Rudi Beyerle , Josef Scholtholt , Rolf-Eberhard Nitz
- 申请人: Heinz Bender , Otto Grawinger , Adolf Stachel, deceased , by Ingeburg Lydia Katharina Stachel, heiress , Rudi Beyerle , Josef Scholtholt , Rolf-Eberhard Nitz
- 申请人地址: DT Frankfurt am Main-Fechenheim
- 专利权人: Cassella Farbwerke Mainkur Aktiengesellschaft
- 当前专利权人: Cassella Farbwerke Mainkur Aktiengesellschaft
- 当前专利权人地址: DT Frankfurt am Main-Fechenheim
- 优先权: DT2339664 19730804
- 主分类号: C07D237/32
- IPC分类号: C07D237/32 ; C07C69/635 ; C07D239/90 ; C07D239/95 ; C07D239/96 ; C07D253/08 ; C07D311/16 ; C07D239/80 ; C07D401/06
摘要:
The present invention relates to new pharmacologically valuable, basically substituted heterocyclic compounds of the formula ##EQU1## wherein X represents--N=N----ch=n-- ##EQU2## R represents an aliphatic, cycloaliphatic, araliphatic or aromatic amine radical having 2 to 10 carbon atoms or the radical of a 5, 6 or 7 ring-membered heterocyclic amine optionally containing an additional N, O or S hetero atom, the radical being attached through the nitrogen atom,R.sub.1 and R.sub.2 represent alkoxy groups containing 1 - 4 C-atoms, R.sub.3 represents lower alkyl having 1 - 3 C-atoms and m and n are 1, 2 or 3.The above derivatives are produced by acylating heterocyclic derivatives having the formula ##STR1## with an alkoxycinnamic acid of the general formula ##STR2## OR A FUNCTIONAL DERIVATIVE OF THE LATTER, OPTIONALLY IN THE PRESENCE OF AN ACID-BINDING AGENT, THE RADICALS R, R.sub.1, R.sub.2, n and m having the meanings set out above.
公开/授权文献
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