发明授权
- 专利标题: Process for preparing cis-chrysanthemic acid
- 专利标题(中): 顺式菊酸的制备方法
-
申请号: US500018申请日: 1974-08-23
-
公开(公告)号: US3989654A公开(公告)日: 1976-11-02
- 发明人: Toshiko Honda , Nobushige Itaya , Akio Higo , Fukashi Horiuchi
- 申请人: Toshiko Honda , Nobushige Itaya , Akio Higo , Fukashi Horiuchi
- 申请人地址: JA Osaka
- 专利权人: Sumitomo Chemical Company, Limited
- 当前专利权人: Sumitomo Chemical Company, Limited
- 当前专利权人地址: JA Osaka
- 优先权: JA48-131988 19731122; JA48-135976 19731130
- 主分类号: C07C61/04
- IPC分类号: C07C61/04
摘要:
A novel process for preparing cis-chrysanthemic acid comprising (1) hydrolysis of trans-.delta.-halogenodihydrochrysanthemic acid or ester thereof under neutrally kept condition with an alkaline earth metal carbonate, (2) conversion of the obtained trans-.delta.-hydroxydihydrochrysanthemic acid ester into a mixture of cis-chrysanthemic acid and iso-cis-chrysanthemic acid by reacting with a strong base, and (3) separation of the cis-chrysanthemic acid from the mixture by selective conversion of the iso-cis-chrysanthemic acid with water in the presence of an acid catalyst into cis-dihydrochrysanthemolactone, followed by separation of the cis-chrysanthemic acid from the lactone with a caustic alkali and an acid.The present process is very useful for converting (-)-trans-chrysanthemic acid which is obtained, as a main remainder of racemic chrysanthemic acid prepared industrially, after (+)-trans-chrysanthemic acid was used for preparation of (+)-trans-chrysanthemic acid ester having a high insecticidal activity, into (+)-cis-chrysanthemic acid which is industrially valuable for preparation of insecticides.
公开/授权文献
- US4508680A Method of manufacturing a rocket combustion chamber 公开/授权日:1985-04-02