发明授权
US4003927A (1-Oxo-7,8-disubstituted-1,2,3,4-tetrahydro-6-naphthyloxy)- and
(3,4-disubstituted-5-oxo-6,7,8,9-tetrahydro-5H-benzocycloheptene-2-yloxy
) acetic acids and derivatives
失效
(1-氧代-7,8-二取代-1,2,3,4-四氢-6-萘氧基) - 和(3,4-二取代-5-氧代-6,7,8,9-四氢-5H- 苯并环庚烯-2-基氧基)乙酸及其衍生物
- 专利标题: (1-Oxo-7,8-disubstituted-1,2,3,4-tetrahydro-6-naphthyloxy)- and (3,4-disubstituted-5-oxo-6,7,8,9-tetrahydro-5H-benzocycloheptene-2-yloxy ) acetic acids and derivatives
- 专利标题(中): (1-氧代-7,8-二取代-1,2,3,4-四氢-6-萘氧基) - 和(3,4-二取代-5-氧代-6,7,8,9-四氢-5H- 苯并环庚烯-2-基氧基)乙酸及其衍生物
-
申请号: US405980申请日: 1973-10-12
-
公开(公告)号: US4003927A公开(公告)日: 1977-01-18
- 发明人: Otto W. Woltersdorf, Jr. , Edward J. Cragoe, Jr. , Everett M. Schultz , Gerald E. Stokker
- 申请人: Otto W. Woltersdorf, Jr. , Edward J. Cragoe, Jr. , Everett M. Schultz , Gerald E. Stokker
- 申请人地址: NJ Rahway
- 专利权人: Merck & Co., Inc.
- 当前专利权人: Merck & Co., Inc.
- 当前专利权人地址: NJ Rahway
- 主分类号: C07C45/28
- IPC分类号: C07C45/28 ; C07C45/41 ; C07C45/46 ; C07C45/67 ; C07C45/68 ; C07C45/71 ; C07C49/747 ; C07C49/755 ; C07C59/64 ; C07C59/72 ; C07C59/90 ; C07C65/03 ; C07C65/21 ; C07D257/04 ; C07C63/595
摘要:
(1-Oxo-7,8-disubstituted-1,2,3,4-tetrahydro-6-naphthyloxy)- and (3,4-disubstituted-5-oxo-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yloxy)acetic acids, their carboxylate salts, and the amide and 5-tetrazole derivatives thereof are active as diuretic and saluretic agents, which also have uricosuric activity.
公开/授权文献
- US5471938A Process for growing multielement compound single crystal 公开/授权日:1995-12-05
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