发明授权
US4006246A Pharmaceutical compositions containing an aminobenzyl-amine and method
of use
失效
含氨基苄基胺的药物组合物及其使用方法
- 专利标题: Pharmaceutical compositions containing an aminobenzyl-amine and method of use
- 专利标题(中): 含氨基苄基胺的药物组合物及其使用方法
-
申请号: US649481申请日: 1976-01-15
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公开(公告)号: US4006246A公开(公告)日: 1977-02-01
- 发明人: Johannes Keck , Klaus-Reinhold Noll , Helmut Pieper , Gerd Kruger , Sigfrid Puschmann
- 申请人: Johannes Keck , Klaus-Reinhold Noll , Helmut Pieper , Gerd Kruger , Sigfrid Puschmann
- 申请人地址: DT Ingelheim am Rhein
- 专利权人: Boehringer Ingelheim GmbH
- 当前专利权人: Boehringer Ingelheim GmbH
- 当前专利权人地址: DT Ingelheim am Rhein
- 优先权: DT2318636 19730413; DT2402989 19740123
- 主分类号: A61K31/135
- IPC分类号: A61K31/135 ; A61K31/19 ; A61K31/24
摘要:
Pharmaceutical dosage unit compositions containing as an active ingredient a compound of the formula ##STR1## wherein R.sub.1 is hydrogen, lower alkanoyl, benzoyl or halobenzoyl,R.sub.2 is hydrogen, chlorine or bromine,R.sub.3 is carboxyl or lower carbalkoxy, andR.sub.4 and R.sub.5 are each hydrogen, alkyl of 1 to 5 carbon atoms, mono- or di-hydroxy-(alkyl of 1 to 5 carbon atoms), alkenyl or 2 to 4 carbon atoms, cycloalkyl of 5 to 7 carbon atoms, mono- or di-hydroxy-(cycloalkyl of 5 to 7 carbon atoms) or benzyl,Or a non-toxic, pharmacologically acceptable acid addition salt thereof; and a method of using the same as anti-ulcerogenics, secretolytics, antitussives, and stimulants of the production of the surfactant or antiatelectasis factor of the alveoli.
公开/授权文献
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