发明授权
US4009328A Aminoglycoside 66-40C, method for its manufacture, method for its use as
an intermediate in the preparation of known antibiotics and novel
antibacterials
失效
氨基糖苷66-40C，其制备方法，其用作制备已知抗生素和新型抗菌剂中的中间体的方法
- 专利标题： Aminoglycoside 66-40C, method for its manufacture, method for its use as an intermediate in the preparation of known antibiotics and novel antibacterials
- 专利标题（中）： 氨基糖苷66-40C，其制备方法，其用作制备已知抗生素和新型抗菌剂中的中间体的方法
-
申请号： US574073申请日： 1975-05-02
-
公开(公告)号： US4009328A公开(公告)日： 1977-02-22
- 发明人: Alan K. Mallams , Richard W. Tkach , David Huw Davies
- 申请人： Alan K. Mallams , Richard W. Tkach , David Huw Davies
- 申请人地址： NJ Kenilworth
- 专利权人： Schering Corporation
- 当前专利权人： Schering Corporation
- 当前专利权人地址： NJ Kenilworth
- 主分类号： C07D209/48
- IPC分类号： C07D209/48 ; C07H15/236 ; C07H15/22
摘要：
Aminoglycoside 66-40C, a minor product produced by the fermentation of Micromonospora inyoensis, is separated from said fermentation mixture, and is used as an intermediate in preparing the known antibiotic, sisomicin, as well as 6' -N-alkylsisomicins having antibacterial activity. Claimed are Aminoglycoside 66-40C as well as 6' -N-t-alkylsisomicins having a tertiary carbon bonded to the 6' -nitrogen.
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