发明授权
- 专利标题： N-(.omega.-Amino)alkylaniline derivatives
- 专利标题（中）： N - （{107 - 氨基）烷基苯胺衍生物
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申请号： US603240申请日： 1975-08-08
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公开(公告)号： US4017624A公开(公告)日： 1977-04-12
- 发明人: Isamu Maruyama , Masaru Nakao , Kikuo Sasajima , Shigeho Inaba , Hisao Yamamoto
- 申请人： Isamu Maruyama , Masaru Nakao , Kikuo Sasajima , Shigeho Inaba , Hisao Yamamoto
- 申请人地址： JA Osaka
- 专利权人： Sumitomo Chemical Company, Limited
- 当前专利权人： Sumitomo Chemical Company, Limited
- 当前专利权人地址： JA Osaka
- 优先权： JA48-15025 19730205
- 主分类号： C07D211/52
- IPC分类号： C07D211/52 ; C07D295/12 ; C07D401/04
摘要：
An N-(.omega.-amino)alkylaniline derivative of the formula: ##STR1## and its pharmaceutically acceptable salts, which are useful as neuroleptic agents and can be prepared by reacting a compound of the formula: ##STR2## with a compound of the formula:H--A[wherein R is hydrogen, C.sub.1 -C.sub.7 alkyl, C.sub.1 -C.sub.7 alkanoyl or aroyl, R.sub.1 is hydrogen, halogen, C.sub.1 -C.sub.7 alkyl or C.sub.1 -C.sub.7 alkoxy,A is ##STR3## (wherein R.sub.2 is hydrogen, halogen, C.sub.1 -C.sub.7 alkyl, C.sub.1 -C.sub.7 alkoxy or trifluoromethyl), ##STR4## (wherein R.sub.2 is as defined above and R.sub.3 is hydrogen, C.sub.1 -C.sub.7 alkyl or C.sub.1 -C.sub.7 alkanoyl), ##STR5## (wherein R.sub.2 is as defined above or ##STR6## (wherein R.sub.2 and R.sub.3 are each as defined above) and n is 2, 3 or 4].