发明授权
- 专利标题: 16-METHYLENE-PROSTAGLANDIN COMPOUNDS
- 专利标题(中): 16-METHYLENE-PROSTAGLANDIN化合物
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申请号: US685953申请日: 1976-05-13
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公开(公告)号: US4018812A公开(公告)日: 1977-04-19
- 发明人: Masaki Hayashi , Seiji Kori , Hajimu Miyake
- 申请人: Masaki Hayashi , Seiji Kori , Hajimu Miyake
- 申请人地址: JA Osaka
- 专利权人: Ono Pharmaceutical Co., Ltd.
- 当前专利权人: Ono Pharmaceutical Co., Ltd.
- 当前专利权人地址: JA Osaka
- 优先权: UK25591/75 19750616
- 主分类号: A61K31/23
- IPC分类号: A61K31/23 ; A61K9/08 ; A61K31/215 ; A61P43/00 ; B01J31/00 ; C07B61/00 ; C07C67/00 ; C07C401/00 ; C07C405/00 ; C07D309/12 ; C08B37/16 ; C12P31/00 ; C07C177/00
摘要:
A compound of the formula: ##STR1## wherein A represents a grouping of the formula: ##STR2## , R.sup.1 represents a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 6 carbon atoms, R.sup.2 represents a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 12 carbon atoms, X represents trans-vinylene or ethylene, and the wavy line indicates attachment of the hydroxy radical in .alpha.- or .beta.-configuration and cyclodextrin clathrates thereof and, when R.sup.2 represents a hydrogen atom, non-toxic salts thereof. These compounds exhibit characteristic prostaglandin activity.
公开/授权文献
- US5182237A Borosilicate glass for electronic flash lamps 公开/授权日:1993-01-26
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