A disc brake for vehicles comprising friction pads adapted to be urged by hydraulic actuator into engagement with opposite faces of a friction disc, the hydraulic actuator having a sliding fit on a stationary part of a vehicle wheel and straddling a peripheral portion of the brake disc together with the pads. The hydraulic actuator is slidingly supported on a pair of parallel guiding pins one of which directly extends from the stationary part while the other pin is removably secured to the stationary part with a sufficient clearance to secure a tolerance extinguishing-ability for the guiding pins and their associated parts.