发明授权
- 专利标题： Thiazolo(5,4-f)quinoline-8-carboxylic acid derivatives
- 专利标题（中）： 噻唑（5,4-f）喹啉-8-羧酸衍生物
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申请号： US661455申请日： 1976-02-25
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公开(公告)号： US4054568A公开(公告)日： 1977-10-18
- 发明人: Hideo Agui , Toru Mitani , Mitsuo Nakashita , Eiichi Murayama , Kousaku Okamura , Takenari Nakagome , Toshiaki Komatsu , Akio Izawa , Yasuko Eda
- 申请人： Hideo Agui , Toru Mitani , Mitsuo Nakashita , Eiichi Murayama , Kousaku Okamura , Takenari Nakagome , Toshiaki Komatsu , Akio Izawa , Yasuko Eda
- 申请人地址： JA Osaka
- 专利权人： Sumitomo Chemical Company, Limited
- 当前专利权人： Sumitomo Chemical Company, Limited
- 当前专利权人地址： JA Osaka
- 优先权： JA48-117042 19731017
- 主分类号： C07D513/04
- IPC分类号： C07D513/04
摘要：
Thiazolo[5,4-f]quinoline-8-carboxylic acid derivatives having either the general formula (I): ##STR1## wherein R.sub.1 is a lower alkyl group, a lower alkenyl group or a benzyl group; or the general formula (III-a): ##STR2## WHEREIN R.sub.3 is a lower alkyl group and X is a halogen atom; and methods for the preparation thereof. The compounds of the general formula (I) are useful as antibacterial agents against gram-negative and gram-positive bacteria. The compounds of the general formula (III-a) are useful as antifungal agents against eumycetes and also as an intermediate in a peparation of the compounds of the general formula (I).