发明授权
US4057633A Compositions and method of using quinolylaminobenzoylpiperazino-1-oxides
失效
喹啉基氨基苯甲酰基哌嗪-1-氧化物的组成和方法
- 专利标题: Compositions and method of using quinolylaminobenzoylpiperazino-1-oxides
- 专利标题(中): 喹啉基氨基苯甲酰基哌嗪-1-氧化物的组成和方法
-
申请号: US715229申请日: 1976-08-18
-
公开(公告)号: US4057633A公开(公告)日: 1977-11-08
- 发明人: Charles E. Coverdale , Louis L. Skaletzky
- 申请人: Charles E. Coverdale , Louis L. Skaletzky
- 申请人地址: MI Kalamazoo
- 专利权人: The Upjohn Company
- 当前专利权人: The Upjohn Company
- 当前专利权人地址: MI Kalamazoo
- 主分类号: A61K31/495
- IPC分类号: A61K31/495 ; A61K31/515 ; A61K31/635
摘要:
Novel compounds of the formula: ##STR1## are disclosed with the corresponding hydrates and pharamceutically acceptable acid addition salts thereof, wherein R.sub.1 is halogen, lower alkyl, or trifluoromethyl; R.sub.2 is lower alkyl, substituted or unsubstituted phenyl or benzyl and R.sub.3 is hydrogen. The novel compounds are useful for the treatment of hypertension and anxiety in mammals, including humans.Disclosed also are compositions containing the novel compounds of the invention and methods of their use in the treatment of hypertension and anxiety.
公开/授权文献
信息查询