发明授权
- 专利标题: 2-Halomethyl-2-nucleophilic substituted methyl penicillins
- 专利标题(中): 2-卤甲基-2-亲核取代的甲基青霉素
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申请号: US762185申请日: 1977-01-24
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公开(公告)号: US4058521A公开(公告)日: 1977-11-15
- 发明人: Shoichiro Uyeo , Tsutomu Aoki , Wataru Nagata
- 申请人: Shoichiro Uyeo , Tsutomu Aoki , Wataru Nagata
- 申请人地址: JA Osaka
- 专利权人: Shionogi & Co., Ltd.
- 当前专利权人: Shionogi & Co., Ltd.
- 当前专利权人地址: JA Osaka
- 优先权: JA51-6960 19760123
- 主分类号: C07D499/42
- IPC分类号: C07D499/42 ; A61K31/397 ; A61K31/43 ; A61P31/04 ; C07D205/08 ; C07D205/095 ; C07D403/12 ; C07D417/12 ; C07D417/14 ; C07D499/00 ; C07D499/21 ; C07D499/44 ; C07D499/46 ; C07D499/60 ; C07D501/10 ; C07D501/16
摘要:
Antibacterial compounds of the formula ##STR1## (where COB is carboxy or protected carboxy;Hal is halogen;R is amino or protected amino;R' is mercapto-protecting group; andX is nucleophilic group)Are prepared from penicillin 1-oxides having X on its 2-methyl group, and found to be used as starting materials for preparing cephalosporins.
公开/授权文献
- US5159265A Pivotable spring contact 公开/授权日:1992-10-27