发明授权
- 专利标题: Imidazo [1,5-a][1,5] benzodiazepines
- 专利标题(中): 咪唑并[8,1-a {9 {8,5 {9 {苯并二氮杂
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申请号: US775347申请日: 1977-03-07
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公开(公告)号: US4080323A公开(公告)日: 1978-03-21
- 发明人: Armin Walser , Rodney Ian Fryer
- 申请人: Armin Walser , Rodney Ian Fryer
- 申请人地址: NJ Nutley
- 专利权人: Hoffmann-La Roche Inc.
- 当前专利权人: Hoffmann-La Roche Inc.
- 当前专利权人地址: NJ Nutley
- 主分类号: A61K31/55
- IPC分类号: A61K31/55 ; A61P21/02 ; A61P25/20 ; C07D243/12 ; C07D487/04
摘要:
The present invention concerns compounds of the formula ##STR1## wherein X is hydrogen or halogen; R.sub.1 is hydrogen, halogen or trifluoromethyl; R.sub.2 is hydrogen or lower alkyl; and R.sub.3 is hydrogen, --COO lower alkyl or CON(R.sub.4).sub.2 wherein R.sub.4 is lower alkyl or hydrogen and may be differentAnd the pharmaceutically acceptable salts thereof.Also provided are methods for the preparation of these compounds as well as pharmaceutical formulations which contain the active compounds of this invention. The compounds of the formula illustrated above are useful as anxiolytics, anticonvulsants, muscle relaxants and sedative agents.
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