发明授权
- 专利标题: 9-[3-(4-Phenoxymethylpiperidino)-propyl]-adenines
- 专利标题(中): 9- {8- 3-(4-苯氧基甲基哌啶子基) - 丙基{9-腺嘌呤
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申请号: US737507申请日: 1976-11-02
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公开(公告)号: US4086347A公开(公告)日: 1978-04-25
- 发明人: Walter-Gunar Friebe , Max Thiel , Kurt Stach, deceased , by Werner Plattner, administrator , Otto-Henning Wilhelms , Erika VON Mullendorff , Gisbert Sponer
- 申请人: Walter-Gunar Friebe , Max Thiel , Kurt Stach, deceased , by Werner Plattner, administrator , Otto-Henning Wilhelms , Erika VON Mullendorff , Gisbert Sponer
- 申请人地址: DT Mannheim-Waldhof
- 专利权人: Boehringer Mannheim GmbH
- 当前专利权人: Boehringer Mannheim GmbH
- 当前专利权人地址: DT Mannheim-Waldhof
- 优先权: DT2550000 19751107
- 主分类号: A61K31/52
- IPC分类号: A61K31/52 ; A61P3/00 ; A61P9/12 ; A61P29/00 ; A61P37/08 ; C07D401/06 ; C07D401/14 ; C07D473/34
摘要:
9-[3-(4-Phenoxymethylpiperidino)-propyl]-adenines of the formula ##STR1## wherein R.sub.1 is a hydrogen atom or a lower alkyl radical,R.sub.2 is a hydrogen atom, a ower alkyl radical optionally substituted by hydroxyl, or a cycloalkyl radical, orR.sub.1 and R.sub.2 together with the nitrogen atom to which they are attached form a heterocyclic ring, andR.sub.3 is a hydrogen atom, a halogen atom, a lower alkyl radical or a lower alkoxy radical,In the form of the free base or a salt thereof, exhibit anti-allergic, anti-inflammatory, anti-oedematous and anti-hypertensive activity.
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