A toothbrush adapted for brushing the teeth of a person or an animal. The handle is cross-sectionally flattened, is S-shaped in orthogonal lateral planes, and is longitudinally twisted to provide an improved grip. The curved handle positions the head at a twisted angle which enables the user to introduce the brush into the mouth of a person, such as a child, or an animal from the side of the mouth. The curved handle also makes it easier to brush the lingual surfaces of the teeth.