发明授权
US4119668A N,N'-Bridged-bis[N,N'substituted-2-hydroxy alkaneammonium] salts
失效
N，N {40-双 - {{N，N {40-取代-2-羟烷基铵{9 {0盐
- 专利标题： N,N'-Bridged-bis[N,N'substituted-2-hydroxy alkaneammonium] salts
- 专利标题（中）： N，N {40-双 - {{N，N {40-取代-2-羟烷基铵{9 {0盐
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申请号： US833485申请日： 1977-09-15
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公开(公告)号： US4119668A公开(公告)日： 1978-10-10
- 发明人: Guy D. Diana , Royal A. Cutler
- 申请人： Guy D. Diana , Royal A. Cutler
- 申请人地址： NY New York
- 专利权人： Sterling Drug Inc.
- 当前专利权人： Sterling Drug Inc.
- 当前专利权人地址： NY New York
- 主分类号： C07C291/04
- IPC分类号： C07C291/04 ; C07C87/30 ; A61K31/14
摘要：
N,N'-Bridged-bis[(O and/or N-substituted)-2-alkyl-2-hydroxyethylamines] of the formula ##STR1## are prepared by condensing an epoxide of the formula ##STR2## and a diamine of the formula R'NH-X-NHR'. The products and dicarbanilates, acid-addition salts, N,N'-dioxides and N,N'-diammonium quaternary salts derived therefrom have antibacterial activity in vitro and are useful as antibacterial agents.