A multi-spindle drill head for use with a machine drive, comprises a main assembly, comprising a first housing member having at least one main spindle which is rotatably supported therein and which is adapted to be connected to the machine drive. A main gear is affixed to the main spindle for rotation therewith and it drives one or more secondary gears on secondary spindles. Each secondary spindle contains a drive pinion which becomes oriented in meshing engagement with a connecting gear which is rotatably mounted on a second housing part which is adapted to be fastened to the first housing part. The connecting gear is rotatably mounted in a position to drive a pinion of a drill spindle. The main spindle itself may contain a lower portion with a drive pinion which may be engaged with a connecting gear to drive the pinion of the drill spindle. One or more spindles may be arranged with an associated connecting gear on the second housing member and the connecting gears of each may be aligned with one or more secondary spindles or the main spindle itself for effecting a drive engagement therebetween.