发明授权
- 专利标题: Process for preparing 1,2,4-triazole derivatives
- 专利标题(中): 制备1,2,4-三唑衍生物的方法
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申请号: US773026申请日: 1977-02-28
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公开(公告)号: US4123437A公开(公告)日: 1978-10-31
- 发明人: Beat Bohner , Dag Dawes , Willy Meyer
- 申请人: Beat Bohner , Dag Dawes , Willy Meyer
- 申请人地址: NY Ardsley
- 专利权人: Ciba-Geigy Corporation
- 当前专利权人: Ciba-Geigy Corporation
- 当前专利权人地址: NY Ardsley
- 优先权: CHX17897/72 19721208
- 主分类号: C07D249/12
- IPC分类号: C07D249/12 ; C07F9/6518 ; C07F9/65
摘要:
1,2,4-TRIAZOLE DERIVATIVES WHICH HAVE PARTICULAR IMPORTANCE AS INTERMEDIATES FOR, E.G., THE PREPARATION OF ACTIVE SUBSTANCES FOR PEST CONTROL, CORRESPONDING TO THE FORMULA ##STR1## wherein R.sup.1 represents an unsubstituted or substituted alkyl, alkenyl, or alkynyl, naphthyl, benzyl, phenylethyl, ##STR2## or phenylpropyl radical, or a mono or polycyclic cycloalkyl radical which can be bound by way of an alkylene bridge member, or a substituted phenyl radical,And new processes for the preparation of compounds of the formula ##STR3## wherein R represents hydrogen, an optionally substituted alkyl, alkenyl or alkynyl radical, an optionally substituted phenyl, naphthyl, benzyl, phenylethyl or phenylpropyl radical, a mono- or polycyclic cycloalkyl radical which can be bound by way of an alkylene bridge member and/or be substituted by alkyl, or a partially hydrogenated naphthyl radical, which processes are performed by addition to a hydrazine of the formulaR -- NH--NH.sub.2or to a hydrazone of the formula ##STR4## wherein R has the above given meaning, R.sub.1 represents hydrogen or lower alkyl and R.sub.2 represents lower alkyl, of an alkoxy-carbonyl-isothiocyanate of the formulaalkyl--O--CO--NCSand subsequent closure of the triazole ring in the resulting thiosemicarbazide of the formula ##STR5## by the splitting-off of an alkanol (alkyl--OH), are disclosed.