发明授权
US4128714A Process for the preparation of 7-acylamida-3-halo-3-alkyl-cepham-4-carboxylic acids and esters 失效
制备7-酰基亚氨基-3-卤代-3-烷基 - 头孢烯-4-羧酸和酯的方法

  • 专利标题: Process for the preparation of 7-acylamida-3-halo-3-alkyl-cepham-4-carboxylic acids and esters
  • 专利标题(中): 制备7-酰基亚氨基-3-卤代-3-烷基 - 头孢烯-4-羧酸和酯的方法
  • 申请号: US654624
    申请日: 1976-02-02
  • 公开(公告)号: US4128714A
    公开(公告)日: 1978-12-05
  • 发明人: Masao KoyamaShigeo Seki
  • 申请人: Masao KoyamaShigeo Seki
  • 申请人地址: JPX Tokyo
  • 专利权人: Meiji Seika Kaisha Ltd.
  • 当前专利权人: Meiji Seika Kaisha Ltd.
  • 当前专利权人地址: JPX Tokyo
  • 优先权: JPX47-36850 19720414
  • 主分类号: C07D501/10
  • IPC分类号: C07D501/10
Process for the preparation of
7-acylamida-3-halo-3-alkyl-cepham-4-carboxylic acids and esters
摘要:
A novel ester of 7-acylamido-3-methyl-cepham-4-carboxylic acid derivative and a process for the preparation thereof which comprises reacting penicillin sulfoxide ester with the metal halide, and a novel 7-acylamido-3-methyl-cepham-4-carboxylic acid derivative and a process for the preparation thereof which comprises reacting penicillin sulfoxide ester with the metal halide and decomposing the resultant in a reductive atmosphere.
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