发明授权
- 专利标题: Crystalline prostanoic acid esters
- 专利标题(中): 结晶前列腺酸酯
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申请号: US826908申请日: 1977-08-19
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公开(公告)号: US4154953A公开(公告)日: 1979-05-15
- 发明人: Werner Skuballa , Bernd Raduchel , Helmut Vorbruggen , Walter Elger , Olaf Loge , Wolfgang Losert
- 申请人: Werner Skuballa , Bernd Raduchel , Helmut Vorbruggen , Walter Elger , Olaf Loge , Wolfgang Losert
- 申请人地址: DEX Berlin and Bergkamen
- 专利权人: Schering Aktiengesellschaft
- 当前专利权人: Schering Aktiengesellschaft
- 当前专利权人地址: DEX Berlin and Bergkamen
- 优先权: DEX2322655 19730503
- 主分类号: C07C405/00
- IPC分类号: C07C405/00 ; C07C177/00
摘要:
Prostanoic acid esters of the formulaPG-- CH.sub.2 -- X-- Ywherein PG is the prostanoyloxy radical of a prostaglandin, X is a carbon-carbon single bond, carbonyl or carbonyloxy, and Y is substituted phenyl are easily crystallized compounds at least as active as the unesterified prostanoic acid and useful for the purification of the parent prostaglandin are prepared by reacting, in the presence of an agent which splits off hydrogen halide, the unesterified prostaglandin with a halide of the formula Hal--CH.sub.2 --X--Y, wherein Hal is a halogen atom and X and Y have the values given above.
公开/授权文献
- US5713157A Deck hanger 公开/授权日:1998-02-03