发明授权
- 专利标题: Haloarylmalonamidooxacephalosporins
- 专利标题(中): 卤代芳基丙酰胺氧基头孢菌素
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申请号: US900235申请日: 1978-04-26
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公开(公告)号: US4183928A公开(公告)日: 1980-01-15
- 发明人: Yoshio Hamashima , Masayuki Narisada , Sadao Hayashi , Wataru Nagata
- 申请人: Yoshio Hamashima , Masayuki Narisada , Sadao Hayashi , Wataru Nagata
- 申请人地址: JPX Osaka
- 专利权人: Shionogi and Co., Ltd.
- 当前专利权人: Shionogi and Co., Ltd.
- 当前专利权人地址: JPX Osaka
- 优先权: JPX52-49630 19770428; JPX52-102260 19770825
- 主分类号: C07D505/06
- IPC分类号: C07D505/06 ; A61K31/5365 ; A61P31/00 ; C07C59/56 ; C07D505/00 ; C07D505/20 ; C07D413/02 ; A61K31/395 ; A61K31/535
摘要:
Antibacterial haloarylmalonamido-1-dethia-1-oxacephalosporins of the following formula: ##STR1## wherein Ar is ##STR2## (in which Hal and Hal' each is halogen and RO is hydroxy or protected hydroxy);COA and COB each is carboxy or protected carboxy including a pharmaceutically acceptable salt group;and Het is 1-lower alkyl-5-tetrazolyl, 1,3,4-thiadiazol-2-yl or 5-lower alkyl-1,3,4-thiadiazol-2-yl,a pharmaceutical or veterinary composition comprising the said haloarylmalonamido-1-dethia-1-oxacephalosporin and pharmaceutical carrier, and a method for treating or preventing human or veterinary infectious diseases comprising administering an effective amount of the said antibacterial compound.
公开/授权文献
- US5983390A Disposable face shield 公开/授权日:1999-11-16
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