发明授权
- 专利标题: Derivatives of 2-oxazolydone and methods for preparing the same
- 专利标题(中): 2-恶唑烷酮的衍生物及其制备方法
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申请号: US905047申请日: 1978-05-11
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公开(公告)号: US4188323A公开(公告)日: 1980-02-12
- 发明人: Vittorio Pestellini , Mario Ghelardoni , Claudio Bianchini , Piero Del Soldato , Giovanna Volterra , Alberto Meli
- 申请人: Vittorio Pestellini , Mario Ghelardoni , Claudio Bianchini , Piero Del Soldato , Giovanna Volterra , Alberto Meli
- 申请人地址: ITX
- 专利权人: A. Menarini S.A.S.
- 当前专利权人: A. Menarini S.A.S.
- 当前专利权人地址: ITX
- 优先权: ITX9578A/77 19770922
- 主分类号: A61K31/42
- IPC分类号: A61K31/42 ; A61K31/421 ; A61P9/08 ; A61P25/02 ; C07D263/20 ; C07D263/24 ; C07D413/12
摘要:
A compound having pharmacological properties comprising the structural formula ##STR1## wherein R is selected from the isopropyl, n-octyl, n-butyl or isobutyl groups; R.sub.1 is selected from the 1-naphthyloxymethyl, (2-allylphenoxy)-methyl, 4-nitrophenyl, {2-[(tetrahydrofurfuryl)oxy-]-phenoxy}-methyl, [4-(2-methoxyethyl)phenoxy]methyl, 4-isopropylthiophenyl, 4-acetaminophenoxymethyl groups; and R.sub.2 represents a hydrogen atom or a methyl group. A method for synthetizing the compound is also disclosed comprising the cyclization of aminoalcohol or halogenurethane.
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