发明授权
- 专利标题： Pregnane derivatives
- 专利标题（中）： 孕烯衍生物
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申请号： US841430申请日： 1977-10-12
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公开(公告)号： US4193921A公开(公告)日： 1980-03-18
- 发明人: Andor Furst , Ludwig Labler , Werner Meier
- 申请人： Andor Furst , Ludwig Labler , Werner Meier
- 申请人地址： NJ Nutley
- 专利权人： Hoffmann-La Roche Inc.
- 当前专利权人： Hoffmann-La Roche Inc.
- 当前专利权人地址： NJ Nutley
- 优先权： CHX13006/76 19761014; CHX11011/77 19770908
- 主分类号： C07J5/00
- IPC分类号： C07J5/00 ; C07J9/00 ; C07J17/00 ; C07J31/00 ; C07J71/00
摘要：
The present invention relates to pregnane derivatives of the formula ##STR1## wherein R.sup.1 and R.sup.3 are hydroxyl groups or readily cleavable etherified or esterified hydroxyl groups and R.sup.20 is hydroxymethyl or readily cleavable etherified or esterified hydroxy methyl, formyl, carboxyl or carbalkoxy useful as intermediates for the preparation of 1.alpha.-hydroxycholecalciferols. The present invention also relates to processes for the preparation of the pregnane derivatives and the intermediates thereof.
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