发明授权
US4205070A 6'N-Alkyl- and 6',6'-di-N-alkyl derivatives of fortimicins A and B
失效
fortimicins A和B的6'N-烷基和6'，6'-二-N-烷基衍生物
- 专利标题： 6'N-Alkyl- and 6',6'-di-N-alkyl derivatives of fortimicins A and B
- 专利标题（中）： fortimicins A和B的6'N-烷基和6'，6'-二-N-烷基衍生物
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申请号： US863018申请日： 1977-12-21
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公开(公告)号： US4205070A公开(公告)日： 1980-05-27
- 发明人: John S. Tadanier , Daniel A. Dunnigan , Leslie A. Freiberg , Jerry R. Martin
- 申请人： John S. Tadanier , Daniel A. Dunnigan , Leslie A. Freiberg , Jerry R. Martin
- 申请人地址： IL North Chicago
- 专利权人： Abbott Laboratories
- 当前专利权人： Abbott Laboratories
- 当前专利权人地址： IL North Chicago
- 主分类号： C07H15/224
- IPC分类号： C07H15/224 ; A61K31/71 ; C07H15/22
摘要：
Novel fortimicin antibiotics represented by the formula ##STR1## wherein R.sub.1 is loweralkyl, R.sub.2 is hydrogen or loweralkyl and R.sub.3 is selected from the group consisting of hydrogen, acyl, hydroxyacyl, aminoacyl, N-monoloweralkylaminoacyl, N,N-diloweralkylaminoacyl, hydroxy-substituted aminoacyl or an aminoacid residue, loweralkyl, hydroxyloweralkyl, aminoloweralkyl, N-monoloweralkylaminoloweralkyl, N,N-diloweralkylaminoloweralkyl or hydroxy-substituted aminoloweralkyl; and the pharmaceutically acceptable salts thereof, intermediates useful in their preparation, compositions employing the compounds and methods of using the compounds.
公开/授权文献
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