发明授权
US4215134A 4-Hydroxy-2-benzimidazoline-thione compounds and pharmaceutical
compositions containing them
失效
4-羟基-2-苯并咪唑啉 - 硫酮化合物和含有它们的药物组合物
- 专利标题: 4-Hydroxy-2-benzimidazoline-thione compounds and pharmaceutical compositions containing them
- 专利标题(中): 4-羟基-2-苯并咪唑啉 - 硫酮化合物和含有它们的药物组合物
-
申请号: US2129申请日: 1979-01-09
-
公开(公告)号: US4215134A公开(公告)日: 1980-07-29
- 发明人: Carl H. Ross , Walter-Gunar Friebe , Wolfgang Kampe , Wolfgang Bartsch , Egon Roesch
- 申请人: Carl H. Ross , Walter-Gunar Friebe , Wolfgang Kampe , Wolfgang Bartsch , Egon Roesch
- 申请人地址: DEX Mannheim
- 专利权人: Boehringer Mannheim GmbH
- 当前专利权人: Boehringer Mannheim GmbH
- 当前专利权人地址: DEX Mannheim
- 优先权: DEX2801980 19780118
- 主分类号: A61K31/415
- IPC分类号: A61K31/415 ; A61K31/4184 ; A61P9/00 ; C07D235/02 ; C07D235/28 ; C07D303/22
摘要:
Novel 4-hydroxy-2-benzimidazoline-thione compound of the formula: ##STR1## wherein R is lower alkyl;R.sub.1 and R.sub.2, which can be the same or different, are hydrogen or lower straight-chained or branched alkyl orR.sub.1 and R.sub.2 together represent alkylene; andR.sub.3 is a hydrogen atom or an acyl radical;and the pharmacologically acceptable salts thereof; have marked .beta.-receptor blocking action and are outstandingly useful in the treatment or prophylaxis of cardiac and circulatory diseases.
公开/授权文献
- USD350846S Cap 公开/授权日:1994-09-27
信息查询