发明授权
US4217360A Novel 1,3-benzodioxaneprostanoic acid derivatives and process for the
preparation thereof
失效
新型1,3-苯并二恶烷庚酸衍生物及其制备方法
- 专利标题: Novel 1,3-benzodioxaneprostanoic acid derivatives and process for the preparation thereof
- 专利标题(中): 新型1,3-苯并二恶烷庚酸衍生物及其制备方法
-
申请号: US2268申请日: 1979-01-10
-
公开(公告)号: US4217360A公开(公告)日: 1980-08-12
- 发明人: Helmut Vorbrueggen , Norbert Schwarz , Olaf Loge , Walter Elger
- 申请人: Helmut Vorbrueggen , Norbert Schwarz , Olaf Loge , Walter Elger
- 申请人地址: DEX Berlin & Bergkamen
- 专利权人: Schering Aktiengesellschaft
- 当前专利权人: Schering Aktiengesellschaft
- 当前专利权人地址: DEX Berlin & Bergkamen
- 优先权: DEX2508826 19750227
- 主分类号: C07C37/62
- IPC分类号: C07C37/62 ; C07C37/66 ; C07D319/08 ; C07F9/655
摘要:
1,3-Benzodioxaneprostanoic acid compound of the formula ##STR1## wherein R.sub.1 is hydroxy, alkoxy of 1-10 carbon atoms, methylsulfamido, substituted or unsubstituted aryloxy, or O--CH.sub.2 --U--V wherein U is a direct bond, carbonyl, or carbonyloxy, and V is phenyl or phenyl substituted, e.g. by one or more of phenyl, phenoxy, alkoxy of 1-2 carbon atoms, and halogen; A is --CH.sub.2 --CH.sub.2 -- or trans --CH.dbd.CH--; B is --CH.sub.2 --CH.sub.2 -- or cis- or trans--CH.dbd.CH--; Z is hydroxymethylene or carbonyl; X Y, if Z is hydroxymethylene, is ##STR2## or, if Z is carbonyl, is ##STR3## or --CH.dbd.CH--; R.sub.2 is hydrogen or alkyl of 1-5 carbon atoms; R.sub.3 and R.sub.4 each are H, F, Cl, Br, I or CF.sub.3, CH.sub.3 or alkoxy of 1-2 carbon atoms or R.sub.3 and R.sub.4 in 6-,7-position is methylendioxy; and if R.sub.1 is hydroxy, salts thereof with pharmaceutically acceptable bases, are agents for inducing menstruation, interrupting pregnancy, inducing labor and synchronizing the sexual cycle in female mammals.
公开/授权文献
- US5927208A CD printer centering adjustment 公开/授权日:1999-07-27
信息查询