发明授权
- 专利标题： Synthesis of substituted phenylacetic acid
- 专利标题（中）： 取代苯乙酸的合成
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申请号： US923351申请日： 1978-07-10
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公开(公告)号： US4220592A公开(公告)日： 1980-09-02
- 发明人: Keiji Kagawa , Naoya Kanda , Fujio Masuko , Hirotoshi Nakanishi
- 申请人： Keiji Kagawa , Naoya Kanda , Fujio Masuko , Hirotoshi Nakanishi
- 申请人地址： JPX Osaka
- 专利权人： Sumitomo Chemical Company, Limited
- 当前专利权人： Sumitomo Chemical Company, Limited
- 当前专利权人地址： JPX Osaka
- 优先权： JPX52/88743 19770722
- 主分类号： C07D317/60
- IPC分类号： C07D317/60 ; C07C51/00 ; C07C51/08 ; C07C57/58 ; C07C67/00
摘要：
A substituted acetonitrile such as .alpha.-isopropyl-p-chlorophenylacetonitrile is hydrolyzed using an acid to produce the corresponding substituted phenylacetic acid such as .alpha.-isopropyl-p-chlorophenylacetic acid in such a manner that, in a lot in any one hydrolysis reaction, (1) the hydrolysis is carried out in at least two steps, (2) an acid to be used in a subsequent first reaction step is a waste acid produced in a previous second reaction step and the subsequent reaction step(s) thereof if any, and (3) an acid to be used in a second reaction step and the subsequent reaction step(s) if any, is the waste acid produced in a previous second reaction step and subsequent reaction step(s), respectively, and a fresh acid.
公开/授权文献
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