发明授权
US4229453A Substituted 5,6-dimethylpyrrolo[2,3-d]pyrimidine compounds, their
production and their medicinal use
失效
取代的5,6-二甲基吡咯并[2,3-d]嘧啶化合物,其生产及其药用
- 专利标题: Substituted 5,6-dimethylpyrrolo[2,3-d]pyrimidine compounds, their production and their medicinal use
- 专利标题(中): 取代的5,6-二甲基吡咯并[2,3-d]嘧啶化合物,其生产及其药用
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申请号: US28028申请日: 1979-04-06
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公开(公告)号: US4229453A公开(公告)日: 1980-10-21
- 发明人: Hermann J. Roth , Kurt Eger , Sedika Issa , Haireddin Jacobi
- 申请人: Hermann J. Roth , Kurt Eger , Sedika Issa , Haireddin Jacobi
- 申请人地址: DEX Leverkusen
- 专利权人: Bayer Aktiengesellschaft
- 当前专利权人: Bayer Aktiengesellschaft
- 当前专利权人地址: DEX Leverkusen
- 优先权: DEX2818676 19780427
- 主分类号: A61K31/505
- IPC分类号: A61K31/505 ; A61P21/02 ; A61P25/04 ; A61P25/08 ; A61P25/20 ; A61P29/00 ; C07D207/34 ; C07D487/04 ; A61K31/495
摘要:
The invention includes 5,6-dimethylpyrrolo [2,3-d]-pyrimidines (and method for their manufacture) of the formula ##STR1## or an acid-addition salt thereof, in which R is amino or hydroxy,R.sub.1 is halogen, nitro, C.sub.1 --C.sub.6 alkyl or alkoxy or CF.sub.3 and, where R is hydroxy, is also hydrogen,R.sub.2 is hydrogen, halogen or C.sub.1 --C.sub.6 -alkyl or alkoxy, andn is 1 or 2.Also included in the invention are pharmaceutical compositions containing said pyrrolo [2,3-d]-pyrimidines and the use of said compounds and compositions for treating CNS illnesses or inflammations.
公开/授权文献
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