发明授权
US4229464A Aminopropanol substituted indole compounds and compositions for the
treatment of cardiac and circulatory diseases
失效
氨基丙醇取代的吲哚化合物和用于治疗心脏和循环系统疾病的组合物
- 专利标题： Aminopropanol substituted indole compounds and compositions for the treatment of cardiac and circulatory diseases
- 专利标题（中）： 氨基丙醇取代的吲哚化合物和用于治疗心脏和循环系统疾病的组合物
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申请号： US943512申请日： 1978-09-18
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公开(公告)号： US4229464A公开(公告)日： 1980-10-21
- 发明人: Wolfgang Kampe , Kurt Stach, deceased , by Werner Plattner, administrator , Max Thiel , Wolfgang Bartsch , Karl Dietmann , Egon Roesch , Wolfgang Schaumann
- 申请人： Wolfgang Kampe , Kurt Stach, deceased , by Werner Plattner, administrator , Max Thiel , Wolfgang Bartsch , Karl Dietmann , Egon Roesch , Wolfgang Schaumann
- 申请人地址： DEX Mannheim
- 专利权人： Boehringer Mannheim GmbH
- 当前专利权人： Boehringer Mannheim GmbH
- 当前专利权人地址： DEX Mannheim
- 优先权： DEX2454406 19741116; DEX2505681 19750211; DEX2508251 19750226; DEX2528771 19750627
- 主分类号： C07D209/43
- IPC分类号： C07D209/43 ; A61K31/40 ; A61K31/403 ; A61K31/404 ; A61P25/02 ; C07D209/08 ; C07D209/12 ; C07D209/32 ; C07D209/42 ; C07D209/18 ; C07D209/20
摘要：
New aminopropanol compounds of the formula ##STR1## wherein R is lower alkyl, cycloalkyl or alkylthioalkyl,R.sub.1 is hydrogen or lower alkyl, hydroxyalkyl, pivaloyloxyalkyl, alkoxyalkyl, alkoxycarbonyl, carboxyl or --CONR.sub.3 R.sub.4, in which R.sub.3 and R.sub.4 which can be the same or different, represent hydrogen or lower alkyl, andR.sub.2 is lower alkyl, hydroxyalkyl, alkoxyalkyl or pivaloyloxyalkyl or, when R is alkylthioalkyl or R.sub.1 is pivaloyloxyalkyl, R.sub.2 can also be hydrogen and the pharmacologically acceptable salts thereof; are outstandingly effective in the treatment or prophylaxis of cardiac and circulatory diseases.
公开/授权文献
- US6032190A System and method for processing data packets 公开/授权日：2000-02-29