发明授权
US4269847A Antiinflammatory-4,5-diphenyl-2-substituted-thio-imidazoles and their
corresponding sulfoxides and sulfones
失效
抗炎-4,5-二苯基-2-取代 - 硫代 - 咪唑及其相应的亚砜和砜
- 专利标题: Antiinflammatory-4,5-diphenyl-2-substituted-thio-imidazoles and their corresponding sulfoxides and sulfones
- 专利标题(中): 抗炎-4,5-二苯基-2-取代 - 硫代 - 咪唑及其相应的亚砜和砜
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申请号: US41367申请日: 1979-05-22
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公开(公告)号: US4269847A公开(公告)日: 1981-05-26
- 发明人: Ulrich Niedballa , Irmgard Bottcher
- 申请人: Ulrich Niedballa , Irmgard Bottcher
- 申请人地址: DEX Berlin and Bergkamen
- 专利权人: Schering Aktiengesellschaft
- 当前专利权人: Schering Aktiengesellschaft
- 当前专利权人地址: DEX Berlin and Bergkamen
- 优先权: DEX2823197 19780524
- 主分类号: A61K31/415
- IPC分类号: A61K31/415 ; A61P29/00 ; C07D233/84 ; C07D233/88 ; C07D401/14 ; C07D405/14 ; C07D409/14
摘要:
Imidazole derivatives of the formula ##STR1## wherein Ar.sub.1 and Ar.sub.2 are each phenyl; phenyl substituted by halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy or C.sub.2-6 dialkylamino; pyridyl; furyl; or thienyl; with the proviso that Ar.sub.1 and Ar.sub.2 are not both unsubstituted phenyl;R.sub.1 is hydrogen, C.sub.1-4 alkyl or C.sub.1-4 alkyl substituted by hydroxy, C.sub.1-4 alkoxy or C.sub.1-6 alkanoyloxy;n is 0, 1 or 2; andZ is a C.sub.2-6 -alkyl or -alkenyl residue substituted by one or two of hydroxy, C.sub.1-4 alkoxy, C.sub.2-8 alkylenedioxy, C.sub.1-6 alkanoyloxy or benzoyloxy, or by one alkoxycarbonyl group;and the salts thereof with physiologically acceptable acids, possess valuable pharmacological properties.
公开/授权文献
- USD375596S Iron sole plate cover 公开/授权日:1996-11-12
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