发明授权
- 专利标题： Halogen derivatives of 8-hydroxycarboxylic acids; the processes for their preparation and medicaments in which they are present
- 专利标题（中）： 8-羟基羧酸的卤素衍生物; 其制备过程及其存在的药物
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申请号： US72411申请日： 1979-09-04
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公开(公告)号： US4287206A公开(公告)日： 1981-09-01
- 发明人: Pierre Simon , Jacques Dreux
- 申请人： Pierre Simon , Jacques Dreux
- 申请人地址： FRX Puteaux
- 专利权人： Laboratoires Hoechst, S.A.
- 当前专利权人： Laboratoires Hoechst, S.A.
- 当前专利权人地址： FRX Puteaux
- 优先权： FRX7825457 19780905
- 主分类号： C07C59/56
- IPC分类号： C07C59/56 ; C07C59/84 ; C07C255/56 ; C07D309/10 ; C07D309/30 ; A61K31/335 ; C07C59/11
摘要：
Halogen derivatives of 8-hydroxycarboxylic acids, which correspond to the formula ##STR1## (open form, in a basic medium) or to the formula ##STR2## (cyclized form, in an acid medium) in which formulae: X.sub.1 and X.sub.2 are halogen atoms, n.sub.1 and n.sub.2 are integers between 0 and 5, but, if n.sub.1 =0, n.sub.2 is different from 0, and vice versa, R is a hydrogen atom or an alkyl or aryl group, and Cation represents an ion originating from a base, or a metal ion, which is pharmaceutically compatible are suitable as antidepressants having a psychostimulant action.
公开/授权文献
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