发明授权
- 专利标题: Demethyl maytansinoids
- 专利标题(中): 去甲基美登木素生物碱
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申请号: US153522申请日: 1980-05-27
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公开(公告)号: US4307016A公开(公告)日: 1981-12-22
- 发明人: Mitsuko Asai , Kazuo Nakahama , Motowo Izawa
- 申请人: Mitsuko Asai , Kazuo Nakahama , Motowo Izawa
- 申请人地址: JPX Osaka
- 专利权人: Takeda Chemical Industries, Ltd.
- 当前专利权人: Takeda Chemical Industries, Ltd.
- 当前专利权人地址: JPX Osaka
- 优先权: JPX53-34645 19780324; JPX53-160787 19781222; JPX54-119959 19790917; KRX2968 19790830
- 主分类号: C07D498/16
- IPC分类号: C07D498/16 ; C12P17/18 ; C07D498/18
摘要:
Novel demethylmaytansinoids representable by the formula: ##STR1## [wherein X is Cl or H; R.sub.1 is H or acyl group] are produced from maytansinoids by means of enzymic transformation. The demethylmaytansinoids are useful as antifungal, antiprotozoal or antitumor agents.
公开/授权文献
- US6103607A Manufacture of MOSFET devices 公开/授权日:2000-08-15
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