发明授权
US4323469A Process for O-acylating phenol derivatives and acylating compositions
for this purpose
失效
用于此目的的O-酰化苯酚衍生物和酰化组合物的方法
- 专利标题： Process for O-acylating phenol derivatives and acylating compositions for this purpose
- 专利标题（中）： 用于此目的的O-酰化苯酚衍生物和酰化组合物的方法
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申请号： US201508申请日： 1980-10-28
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公开(公告)号： US4323469A公开(公告)日： 1982-04-06
- 发明人: Gyorgy Lugosi , Antal S. May , Janos Bodnar , Istvan Turcsan , Istvan Jelinek , Eva Somfai , Laszlo Simandi
- 申请人： Gyorgy Lugosi , Antal S. May , Janos Bodnar , Istvan Turcsan , Istvan Jelinek , Eva Somfai , Laszlo Simandi
- 申请人地址： HUX Budapest
- 专利权人： Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.
- 当前专利权人： Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.
- 当前专利权人地址： HUX Budapest
- 主分类号： C07D307/86
- IPC分类号： C07D307/86 ; C09K3/00
摘要：
The invention relates to a process for the preparation of carbamic acid phenyl esters of the formula (I) ##STR1## by acylating phenol derivatives of the formula (II) ##STR2## wherein R is alkyl having 1 to 8 carbon atoms, aryl, cycloalkyl having 5 or 6 carbon atoms, aralkyl having 7 to 16 carbon atoms which groups can be substituted by one or more alkyl groups,R.sup.1 is hydrogen, alkyl having 1 to 4 carbon atoms, alkoxy having 1 to 4 carbon atoms or acylamino,R.sup.2 is hydrogen, halogen, alkyl having 1 to 4 carbon atoms or alkoxy having 1 to 4 carbon atoms, or ifR.sup.1 and R.sup.2 represent alkyl and/or alkoxy, they can form together a carbocyclic ring.According to the invention the phenol derivatives of the general formula (II), wherein R.sup.1 and R.sup.2 are as defined above, are reacted with N-carbamoyl-saccharin derivatives of the formula (IV) ##STR3## wherein R has the same meaning as defined above, in the presence of a base.